Location: Boston, MA
The Biostatistician I collaborates with senior statisticians and medical researchers on US domestic and multinational clinical trials and other research studies. Our current focus is on studies of treatments for HIV and other infectious diseases, with potential to expand into other areas of clinical research. The Biostatistician I may have the opportunity to participate in research that makes significant contributions to the treatment of children infected with HIV and other pathogens. Examples of other potential clinical areas are: to elucidate host and bacterial factors resulting in protection against TB infection and disease, and to examine novel TB biomarkers using samples from biorepositories coupled with existing clinical data.
Major Duties and Responsibilities
- Act as protocol statistician collaborating with medical researchers in the design, implementation, monitoring, analysis and publication of results from US domestic and multinational clinical trials and observational studies of treatments for HIV and other infectious diseases.
- Participate in peer review/critique of reports and analyses.
- Maintain professional knowledge and expertise.
- Perform the following specific duties under the direction of a senior statistician:
- Conduct ongoing, periodic and final analyses of data, using specialized statistical techniques and statistical programming. Determine proper summary statistics, report formats and address all other analysis considerations.
- Review the proposed study methodology, study parameters and related study features of proposals and protocols, to ensure conformance with accepted statistical principles. Recommend revisions and modifications.
- Develop stratification and randomization materials.
- Collaborate with data managers on the development of data collection forms and proposed data management methods to ensure that the data to be collected will meet study objectives and allow valid analyses.
- Ensure integrity of data collection, data review, data compilation and analysis by monitoring protocols and procedures to ensure compliance with proper statistical techniques.
- Prepare periodic and ad hoc study data status reports.
- Collaborate with clinicians, senior statisticians and other protocol team members on manuscripts, abstracts and other publications documenting study findings.
Reports to: Initially reports to Lead Statistician for Pediatric Studies, with the possibility of becoming involved with non-pediatric projects in the future.
- Master's Degree in Biostatistics, Statistics, or a closely related field.
- Work experience and/or education in statistical analysis of clinical or biological data is desirable, but recent graduates will be considered.
- Experience with MS Office (Word, Excel, PowerPoint).
- Programming skills in SAS preferred; skills in another statistical computing language will be considered.
- Excellent oral and written communication skills, with the ability to effectively collaborate with study chairs, medical officers, protocol specialists and database managers.
- Experience in Phase I/dose-finding studies, regulatory submissions, and/or constructing/handling CDISC datasets is helpful.
Email resume/cover letter to email@example.com and include BioStat1_20190308 in the subject line.
All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, disability, or veteran status.