Dr. Karkaletsis is the Director of the Institute of Informatics & Telecommunications at NCSR Demokritos,  and a member of the High Level Advisory Committee on AI to the Greek Prime Minister. Also member of the National Commission for Bioethics & Technoethics and the Expert Group on AI Incidents at OECD.AI.

Previously Member of the National Council for Research and Innovation (ESETEK) and Head of the Software & Knowledge Engineering Lab (SKEL The AI Lab) at IIT. Coordinator, scientific and technical manager of many European and national projects and organiser of numerous scientific international conferences, workshops and summer schools. Responsible for the Institute’s educational activities for more than 10 years, initiated the joint PhD scholarship programme with several Universities abroad, launched the new MSc in Data Science and MSc in Artificial Intelligence programmes for NCSR Demokritos, and set up the new educational programme for primary and secondary schools. Research interests are in the areas of Artificial Intelligence, content analysis, big data management, knowledge representation, human-machine interaction.